| ID | DRAMP01840 |
|---|---|
| Sequence | GFRDVLKGAAKAFVKTVAGHIAN |
| Length | 23 |
| Name | Ascaphin-1 (Frogs, amphibians, animals) |
| Source | Ascaphus truei (Coastal tailed frog) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.15207717]Gram-negative bacterium: Escherichia coli (MIC=6 µM);##Gram-positive bacterium: Staphylococcus aureus (MIC>50 µM). |
| Hemolytic Activity | [Ref.15207717]HC50>200 μM against human erythrocytes |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | P0CJ25 |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 15207717 |
Physicochemical Properties
| Residues | 23 |
|---|---|
| Sequence | GFRDVLKGAAKAFVKTVAGHIAN |
| Molecular Weight | 2370.75 |
| Grand Average of Hydropathy | 0.313 |
| Isoelectric Point | 10.29 |
| Charge at pH 7.4 | 2.587 |
| Secondary Structure | Helix: 0.304, Turn: 0.174, Sheet: 0.261 |
| Instability Index | 16.343 |
| Aromaticity | 0.087 |