Basic Information

IDDRAMP01081
SequenceGLKDIFKAGLGSLVKGIAAHVAN
Length23
NameAlyteserin-1a (toads, amphibians, animals)
SourceAlytes obstetricans (European midwife toad)
ActivityAntimicrobial, Antibacterial, Anti-Gram-
Pathogen[Ref.19463738]Gram-negative bacterium: Escherichia coli (MIC=25 µM).
Hemolytic Activity[Ref:19463738] LC50 > 100 μM against human erthrocytes. Alyteserin-1a induced a hemolysis of 11% at the concentration of 100 μM.
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal Modificationα-Amidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID19463738

Physicochemical Properties

Residues23
SequenceGLKDIFKAGLGSLVKGIAAHVAN
Molecular Weight2279.679
Grand Average of Hydropathy0.63
Isoelectric Point9.703
Charge at pH 7.41.587
Secondary StructureHelix: 0.348, Turn: 0.261, Sheet: 0.304
Instability Index-12.987
Aromaticity0.043

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.