| ID | DRAMP01085 |
|---|---|
| Sequence | GLKEIFKAGLGSLVKGIAAHVAS |
| Length | 23 |
| Name | Alyteserin-1c (toads, amphibians, animals) |
| Source | Alytes obstetricans (Common midwife toad) (Bufo obstetricans) |
| Activity | Antimicrobial, Antibacterial, Anti-Gram- |
| Pathogen | Gram-negative bacterium: Escherichia coli (MIC=25 µM). |
| Hemolytic Activity | [Ref:19463738] LC50 = 145 μM against human erthrocytes. |
| Cytotoxicity | No cytotoxicity information found |
| N-terminal Modification | Free |
| C-terminal Modification | α-Amidation |
| Linear/Cyclic/Branched | Linear |
| Uniprot | H0USY4 |
| PDB | 2L5R |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 21565166, 19463738 |
Physicochemical Properties
| Residues | 23 |
|---|---|
| Sequence | GLKEIFKAGLGSLVKGIAAHVAS |
| Molecular Weight | 2266.681 |
| Grand Average of Hydropathy | 0.748 |
| Isoelectric Point | 9.703 |
| Charge at pH 7.4 | 1.588 |
| Secondary Structure | Helix: 0.348, Turn: 0.261, Sheet: 0.348 |
| Instability Index | -4.613 |
| Aromaticity | 0.043 |