Basic Information

IDDRAMP01607
SequenceGLFDIIKKIAESF
Length13
NameAurein-1.2 (Frogs, amphibians, animals)
SourceLitoria raniformis (Southern bell frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Anti-cancer
PathogenGram-positive bacteria: Bacillus cereus (MIC=100 μg/ml), Leuconostoc lactis (MIC=12 μg/ml), Listeria innocua (MIC=100 μg/ml), Micrococcus luteus (MIC=100 μg/ml), Staphylococcus epidermidis (MIC=50 μg/ml), Streptococcus uberis (MIC=50 μg/ml), Staphylococcus aureus (MIC=8 μmol/L);##Gram-negative bacteria: Pasteurella multocida (MIC=100 μg/ml), Escherichia coli (MIC=8 μmol/L);##Fungi: Candida albicans (MIC=32 μmol/L)
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.10951191]No cytotoxicity information found##[Ref.15572363]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot P82387
PDB 1VM5
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10951191, 15572363, 15203252

Physicochemical Properties

Residues13
SequenceGLFDIIKKIAESF
Molecular Weight1480.746
Grand Average of Hydropathy0.669
Isoelectric Point6.069
Charge at pH 7.4-0.446
Secondary StructureHelix: 0.462, Turn: 0.154, Sheet: 0.231
Instability Index20.477
Aromaticity0.154

Similar Structure Search

Candidates based on structure

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