| ID | DRAMP03999 |
|---|---|
| Sequence | ILGKIAEGIKSLF |
| Length | 13 |
| Name | [A6]-IsCT (Mutant: W6A; IsCT analog) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.15369808]Gram-negative bacteria: Escherichia coli KCTC 1682 (MIC=64 µM), Pseudomonas aeruginosa KCTC 1637 (MIC=32 µM), Salmonella typhimurium KCTC 1926 (MIC>64 µM);##Gram-positive bacteria: Staphylococcus epidermidis KCTC 1917 (MIC>64 µM), Staphylococcus aureus KCTC 1621 (MIC>64 µM). |
| Hemolytic Activity | [Ref.15369808]Non-hemolytic activity |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 15369808 |
Physicochemical Properties
| Residues | 13 |
|---|---|
| Sequence | ILGKIAEGIKSLF |
| Molecular Weight | 1388.693 |
| Grand Average of Hydropathy | 0.985 |
| Isoelectric Point | 8.591 |
| Charge at pH 7.4 | 0.554 |
| Secondary Structure | Helix: 0.462, Turn: 0.231, Sheet: 0.308 |
| Instability Index | -2.077 |
| Aromaticity | 0.077 |