Basic Information
| ID | DRAMP18189 |
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| Sequence | IFGAIWKGISSLL |
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| Length | 13 |
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| Name | Pantinin-2 (Non-disulfide-bridged peptide 4.21, NDBP-4.21, Non-disulfide-bridged peptide 5.22, ND |
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| Source | Pandinus imperator (Emperor scorpion) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.23624072]Gram-positive bacteria: S.aureus (MIC=48 μM), B.magaterium (MIC=36 μM), M.luteus (MIC=18 μM ), VRE (MIC=36 μM), MRSA (MIC=28 μM);##Gram-negative bacteria: E.coli (MIC=48 μM), P.putida (MIC >87 μM), K.oxytoca (MIC >87 μM), E.cloacae (MIC >87 μM), S.enterica (MIC=68 μM);##Fungus: C.tropicalis (MIC=16 μM). |
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| Hemolytic Activity | [Ref.23624072]10% hemolytic activity at 16 μM, 80% hemolytic activity at 32 μM, 100% hemolytic activity at 64 μM against human red bood cells |
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| Cytotoxicity | Not included yet |
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| N-terminal Modification | Not included yet |
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| C-terminal Modification | Not included yet |
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| Linear/Cyclic/Branched | Not included yet |
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| Uniprot |
R4JQZ0 |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 23624072, 24184590 |
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