| ID | DRAMP20831 |
|---|---|
| Sequence | ILGKLWEGLKSLF |
| Length | 13 |
| Name | IsCT1L1 |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | [Ref.28657596] Gram-positive bacteria:Staphylococcus aureus (MIC=50μg/mL);##Gram-negative bacteria: S. typhimurium (MIC=100μg/mL), Escherichia coli (MIC=50μg/mL) |
| Hemolytic Activity | [Ref.28657596] 1% hemolysis at 10 μg/ml, 78% hemolysis at 50 μg/ml, 90% hemolysis at 100 μg/ml against human red cells |
| Cytotoxicity | [Ref.28657596] No cytotoxicity information found |
| N-terminal Modification | Free |
| C-terminal Modification | Amidation |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 28657596 |
Physicochemical Properties
| Residues | 13 |
|---|---|
| Sequence | ILGKLWEGLKSLF |
| Molecular Weight | 1503.825 |
| Grand Average of Hydropathy | 0.669 |
| Isoelectric Point | 8.591 |
| Charge at pH 7.4 | 0.554 |
| Secondary Structure | Helix: 0.538, Turn: 0.231, Sheet: 0.385 |
| Instability Index | 22.669 |
| Aromaticity | 0.154 |