| ID | DRAMP04001 |
|---|---|
| Sequence | ILGKIWKGIKSLF |
| Length | 13 |
| Name | [K7]-IsCT (Mutant: E7K; IsCT analog) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
| Pathogen | Gram-negative bacteria: Escherichia coli KCTC 1682 (MIC=2 µM), Pseudomonas aeruginosa KCTC 1637 (MIC=2 µM), Salmonella typhimurium KCTC 1926 (MIC=1 µM);##Gram-positive bacteria: Staphylococcus epidermidis KCTC 1917 (MIC=1 µM), Staphylococcus aureus KCTC 1621 (MIC=1 µM) |
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 15369808 |
Physicochemical Properties
| Residues | 13 |
|---|---|
| Sequence | ILGKIWKGIKSLF |
| Molecular Weight | 1502.884 |
| Grand Average of Hydropathy | 0.746 |
| Isoelectric Point | 10.302 |
| Charge at pH 7.4 | 2.55 |
| Secondary Structure | Helix: 0.538, Turn: 0.231, Sheet: 0.154 |
| Instability Index | -8.608 |
| Aromaticity | 0.154 |