Basic Information

IDDRAMP04000
SequenceILGKILEGIKSLF
Length13
Name[L6]-IsCT (Mutant: W6L; IsCT analog)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacteria: Escherichia coli KCTC 1682 (MIC=16 µM), Pseudomonas aeruginosa KCTC 1637 (MIC=16 µM), Salmonella typhimurium KCTC 1926 (MIC=16 µM);##Gram-positive bacteria: Staphylococcus epidermidis KCTC 1917 (MIC=32 µM), Staphylococcus aureus KCTC 1621 (MIC=4 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15369808

Physicochemical Properties

Residues13
SequenceILGKILEGIKSLF
Molecular Weight1430.773
Grand Average of Hydropathy1.138
Isoelectric Point8.591
Charge at pH 7.40.554
Secondary StructureHelix: 0.538, Turn: 0.231, Sheet: 0.308
Instability Index12.738
Aromaticity0.077

Similar Structure Search

Candidates based on structure

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