Basic Information
| ID | DRAMP21228 |
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| Sequence | ILKKIWKaIKKLF |
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| Length | 13 |
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| Name | IsCT-a (Derived from IsCT-P) |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.16871429] Gram-positive bacteria : Staphylococcus aureus (KCTC 1621)(MIC=1 μM), Bacillus subtilis (KCTC 3068)(MIC=2 μM), Staphylococcus epidermidis (KCTC 1917)(MIC=1 μM), MRSA (CCARM 3001)(MIC=2 μM), MRSA (CCARM 3543)(MIC=1 μM);##Gram-negative bacteria : Escherichia coli (KCTC 1682)(MIC=2 μM), Pseudomonas aeruginosa (KCTC 1637)(MIC=2 μM), Salmonella typhimurium (KCTC 1926)(MIC=2 μM), MDRPA (CCARM 2095)(MIC=2 μM) |
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| Hemolytic Activity | [Ref.16871429] HC50>400 μM against human red blood cells |
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| Cytotoxicity | [Ref.16871429] No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 16871429 |
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