Basic Information
| ID | DRAMP01420 |
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| Sequence | GLLSGILGAGKHIICGLSGLC |
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| Length | 21 |
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| Name | Nigrocin-OG4 (Frogs, amphibians, animals) |
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| Source | Odorrana grahami (Yunnanfu frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | Gram-negative bacterium: Escherichia coli (MIC>100 µg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC>100 µg/ml), Bacillus subtilis (MIC>100 µg/ml).##Yeast: Candida albicans (MIC=1.10 µg/ml). |
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| Hemolytic Activity | [Ref.17272268] RCH=65.5 ± 7.7% against rabbit red blood cells at 50 μg/ml. RCH, red cell hemolysis. |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Cyclization (Cys15 and Cys21) |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 17272268 |
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