Basic Information

IDDRAMP18655
SequenceVGTIIKIIKAIIDIFAK
Length17
NamedPSMα4 (PSMα4 peptide derivative; bacteriocin; staphylococcus aureus, bacteria)
SourceTruncated the peptide PSMα4 (from Staphylococcus aureus)
ActivityAntimicrobial, Antibacterial, Anti-Gram+
Pathogen[Ref.22371493]Gram-positive bacteria: Streptococcus serotype GAS M3 strain 4041-05 (MIC=10 μM).
Hemolytic Activity[Ref.22371493]52% hemolysis at 10μg/mL against human red blood cells
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot A9JX08, P0C827, P0C826, P0C825, P0C824, P0C823, P0C822, P0C821, P0C820
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22371493

Physicochemical Properties

Residues17
SequenceVGTIIKIIKAIIDIFAK
Molecular Weight1856.339
Grand Average of Hydropathy1.518
Isoelectric Point9.703
Charge at pH 7.41.516
Secondary StructureHelix: 0.529, Turn: 0.059, Sheet: 0.118
Instability Index-15.559
Aromaticity0.059

Similar Structure Search

Candidates based on structure

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