Basic Information

IDDRAMP02347
SequenceGKGRWLERIGKAGGIIIGGALDHL
Length24
NameNRC-1 (fish, chordates, animals)
SourcePseudopleuronectes americanus (Winter flounder 1)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Aeromonas salmonicida 99-1 (MIC=64 µg/ml), Aeromonas salmonicida 97-4 (MIC=64 µg/ml), Salmonella enterica serovar Typhimurium MS7953s (MIC=16 µg/ml), Salmonella enterica serovar Typhimurium 14028s (MIC>64 µg/ml), Pseudomonas aeruginosa K799 (MIC>64 µg/ml), Pseudomonas aeruginosa Z61 (MIC=32 µg/ml), Escherichia coli CGSC 4908 (MIC=32 µg/ml), Escherichia coli UB1005 (MIC=32 µg/ml), Escherichia coli DC2 (MIC=32 µg/ml);##Gram-positive bacteria: Staphylococcus epidermidis C621 (MIC>64 µg/ml), Staphylococcus aureus (MRSA) C623 (MIC>64 µg/ml).##Yeast: Candida albicans C627 (MIC=64 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID12878506

Physicochemical Properties

Residues24
SequenceGKGRWLERIGKAGGIIIGGALDHL
Molecular Weight2487.9
Grand Average of Hydropathy0.096
Isoelectric Point9.986
Charge at pH 7.41.591
Secondary StructureHelix: 0.333, Turn: 0.292, Sheet: 0.250
Instability Index31.188
Aromaticity0.042

Similar Structure Search

Candidates based on structure

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