Basic Information

IDDRAMP02771
SequenceFDITKLNIKKLTKATCKVISKGASMCKVLFDKKKQE
Length36
NamePilosulin 4 (ants, insects, animals)
SourceMyrmecia banksi (Jack jumper ant) (Australian jumper ant)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.15246874]Gram-positive bacteria: Staphylococcus aureus (MIC<6.25 µM), Bacillus subtilis (MIC<50 µM);##Gram-negative bacteria: Pseudomonas aeruginosa (MIC<25 µM), Escherichia coli (MIC<6.25 µM).
Hemolytic Activity[Ref.15246874]Non-hemolytic activity at 50 μM against human whole blood
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot Q68Y22
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15246874

Physicochemical Properties

Residues36
SequenceFDITKLNIKKLTKATCKVISKGASMCKVLFDKKKQE
Molecular Weight4086.969
Grand Average of Hydropathy-0.311
Isoelectric Point9.867
Charge at pH 7.46.487
Secondary StructureHelix: 0.278, Turn: 0.111, Sheet: 0.194
Instability Index21.833
Aromaticity0.056

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