Basic Information

IDDRAMP00172
SequenceLVATGMAAGVAKTIVNAVSAGMDIATALSLFSGAFTAAGGIMALIKKYAQKKLWKQLIAA
Length60
NameGarvicin ML (Bacteriocin)
SourceLactococcus garvieae DCC43 (Gram-positive bacteria)
ActivityAntimicrobial, Antibacterial, Anti-Gram+
PathogenGram-positive bacteria: Lactobacillus reuteri 20016 (378), L. helveticus 15009 (492), L. curvatus 2739 (177), L. casei 334 (1-174), L. acidophilus 4356 (236), L. sakei 2714 (1-445), Lactococcus lactis BB24 (928), L. lactis NZ9000 (163), L. lactis DPC5598 (1-541)，L. garvieae 5274 (617), L. garvieae 5806 (2-807), L. garvieae 5807 (2-705), L. raffinolactis 988 (228), Pediococcus acidilactici 347 (1-398), P. pentosaceus FBB61 (1-131), Enterococcus faecium P13 (1-291), E. faecium L50 (719), E. faecialis DBH18 (25), E. faecalis P4 (123), Propionibacterium sp.P6 (190), P. acidipropionici 563 (864), Clostridium tyrobutiricum 3.5CT (651), C. tyrobutiricum 1754 (839), C. perfringens 376 (352), C. botulinum 551 (574), Listeria monocytogenes 4032 (662), L. ivanovii 913 (1-020), L. seeligeri 917 (684), L. grayi 931 (742), L. welshimeri 919 (452), Brochothrix thermosphacta 847 (283), Streptococcus pneumoniae FQ26 (590), S. pneumoniae 67620 (596), S. pneumoniae 15M-1047 (790).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationNo specific N-terminal
C-terminal ModificationNo specific C-terminal
Linear/Cyclic/BranchedCyclic
Uniprot D2KC49
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID21057028

Physicochemical Properties

Residues60
SequenceLVATGMAAGVAKTIVNAVSAGMDIATALSLFSGAFTAAGGIMALIKKYAQKKLWKQLIAA
Molecular Weight6025.198
Grand Average of Hydropathy0.887
Isoelectric Point10.126
Charge at pH 7.44.54
Secondary StructureHelix: 0.317, Turn: 0.167, Sheet: 0.400
Instability Index19.347
Aromaticity0.067

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Candidates based on structure

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