Basic Information
| ID | DRAMP01668 |
|---|
| Sequence | ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQ |
|---|
| Length | 34 |
|---|
| Name | Dermaseptin-1 (DS I; Dermaseptin-S1, DS1; Frogs, amphibians, animals) |
|---|
| Source | Phyllomedusa sauvagei (Sauvage's leaf frog) |
|---|
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiprotozoal |
|---|
| Pathogen | Fungi: Microsporum canis (IP 1194) (MIC=50 µg/ml), Tricophyton rubrum (IP 1400-82) (MIC=100 µg/ml), Arthroderma simii (IP 1063-74) (MIC=100 µg/ml), Aspergillus fumigatus (IP 1025-70) (MIC=100 µg/ml), Aerornonas caviae IP (67-16) T (MIC=50 µg/ml), Cryptococcus neoformans (IP 960-67) (MIC=15 µg/ml), Cryptococcus neoformans (IP 962-67) (MIC=15 µg/ml), Candida albicans (IP 884-65) (MIC=60 µg/ml); ##Gram-negative bacterium: Escherichia coli (IP 76-24) (MIC=5 µg/ml);##Gram-positive bacterium: Nocardia brasiliensis (IP 16-80) (MIC=200 µg/ml). |
|---|
| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
|---|
| Cytotoxicity | [Ref.1909573]No cytotoxicity information found##[Ref.8306981]No cytotoxicity information found |
|---|
| N-terminal Modification | Free |
|---|
| C-terminal Modification | Free |
|---|
| Linear/Cyclic/Branched | Linear |
|---|
| Uniprot |
P24302, P80277 |
|---|
| PDB |
|
|---|
| 3D View | |
|---|
| PDB Download | Download PDB Predicted by Alphafold2 |
|---|
| PubMed ID | 1909573, 8306981 |
|---|
