Basic Information

IDDRAMP01259
SequenceALWKTMLKKLGTMALHAGKAAFGAAADTISQ
Length31
NameDermadistinctin-M (DD M; Frogs, amphibians, animals)
SourcePhyllomedusa distincta (Monkey frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Staphylococcus aureus (MIC=38 µM), Enterococcus faecalis (MIC>38 µM);##Gram-negative bacteria: Pseudomonas aeruginosa (MIC=38 µM), Escherichia coli (MIC=9.7 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.10477123]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedLinear
Uniprot P83640
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10477123

Physicochemical Properties

Residues31
SequenceALWKTMLKKLGTMALHAGKAAFGAAADTISQ
Molecular Weight3202.79
Grand Average of Hydropathy0.319
Isoelectric Point10.002
Charge at pH 7.42.635
Secondary StructureHelix: 0.226, Turn: 0.129, Sheet: 0.452
Instability Index6.229
Aromaticity0.065

Similar Structure Search

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