Basic Information
| ID | DRAMP01520 |
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| Sequence | GLLNTFKDWAISIAKGAGKGVLTTLSCKLDKSC |
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| Length | 33 |
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| Name | Rugosin-A (Frogs, amphibians, animals) |
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| Source | Glandirana rugosa (Japanese wrinkled frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | Gram-positive bacteria: Staphylococcus aureus 209P (MIC=6.25 µg/ml), Bacillus subtilis ATCC6633 (MIC=12.5 µg/ml), Micrococcus luteus ATCC9341 (MIC=25 µg/ml), Streptococcus pyogenes COOK (MIC=50 µg/ml);##Gram-negative bacteria: Escherichia coli NIHJ (MIC=100 µg/ml), Pseudomonas aeruginosa PAO-1 (MIC>100 µg/ml). |
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| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
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| Cytotoxicity | [Ref.7612013]No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Cyclization (Cys27 and Cys33) |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
P80954 |
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| PDB |
|
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 7612013 |
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