Basic Information

IDDRAMP01953
SequenceGLLDSLKNLAINAAKGAGQSVLNTLSCKLSKTC
Length33
NameBrevinin-2HSa (Frogs, amphibians, animals)
SourceOdorrana hosii (Hose's rock frog) (Rana hosii)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=18 µM);##Gram-negative bacterium: Escherichia coli ATCC 25726 (MIC=36 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys27 and Cys33)
Linear/Cyclic/BranchedCyclic
Uniprot P0C8S9
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID18621071

Physicochemical Properties

Residues33
SequenceGLLDSLKNLAINAAKGAGQSVLNTLSCKLSKTC
Molecular Weight3332.889
Grand Average of Hydropathy0.261
Isoelectric Point9.308
Charge at pH 7.42.499
Secondary StructureHelix: 0.273, Turn: 0.303, Sheet: 0.333
Instability Index25.864
Aromaticity0

Similar Structure Search

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