Basic Information

IDDRAMP01929
SequenceGILLDKLKNFAKTAGKGVLQSLLNTASCKLSGQC
Length34
NameBrevinin-2Ec (Frogs, amphibians, animals)
SourceRana esculenta (Edible frog) (Pelophylax esculentus) (Rana saharica (Sahara frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Swiss_Prot Entry P40839]Shows antibacterial activity against representative Gram-negative and Gram-positive bacterial species
Hemolytic Activity[Ref.8163497]LC50>100 µM against human erythrocytes
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P40839, P84842
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID8163497, 16394170

Physicochemical Properties

Residues34
SequenceGILLDKLKNFAKTAGKGVLQSLLNTASCKLSGQC
Molecular Weight3521.158
Grand Average of Hydropathy0.179
Isoelectric Point9.595
Charge at pH 7.43.496
Secondary StructureHelix: 0.294, Turn: 0.265, Sheet: 0.294
Instability Index20.856
Aromaticity0.029

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