Basic Information

IDDRAMP02104
SequenceGLMSTLKDFGKTAAKEIAQSLLSTASCKLAKTC
Length33
NameBrevinin-2RTa (Frogs, amphibians, animals)
SourceAmolops ricketti (Chinese sucker frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.22100518]Gram-positive bacteria: Staphylococcus aureus ATCC2592 (MIC=12.5 µg/ml), Bacillus licheniformis X39 (MIC=50.0 µg/ml), Staphylococcus carnosus KHS (MIC=6.3 µg/ml), Rhodococcus rhodochrous X15 (MIC=1.6 µg/ml);##Gram-negative bacteria: Serratia rubidaea X01 (MIC=100.0 µg/ml), Psychrobacter faecalis X29 (MIC=6.3 µg/ml).
Hemolytic Activity[Ref.22100518]LD50>400 μg/ml against rabbit red blood cells
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22100518

Physicochemical Properties

Residues33
SequenceGLMSTLKDFGKTAAKEIAQSLLSTASCKLAKTC
Molecular Weight3417.025
Grand Average of Hydropathy0.164
Isoelectric Point9.243
Charge at pH 7.42.497
Secondary StructureHelix: 0.212, Turn: 0.182, Sheet: 0.364
Instability Index42.039
Aromaticity0.03

Similar Structure Search

Candidates based on structure

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