Basic Information
| ID | DRAMP02084 |
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| Sequence | GIMDTLKNLAKTAGKGALQSLLNKASCKLSGQC |
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| Length | 33 |
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| Name | Brevinin-2E (Frogs, amphibians, animals) |
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| Source | Rana esculenta (Edible frog) (Pelophylax esculentus) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.8508915]Gram-positive bacteria: Bacillus megaterium Bm11 (MIC=0.2 µM), Staphylococcus aureus Cowan 1 (MIC=2.0 µM);##Gram-negative bacteria: Escherichia coli D21 (MIC=0.5 µM), Pseudomonas aeruginosa ATCC 15692 (MIC>30 µM). |
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| Hemolytic Activity | [Ref.8163497]LC50>100 μM against human red blood cells |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Cyclization (Cys27 and Cys33) |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
P32413 |
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| PDB |
|
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 8508915 |
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