Basic Information

IDDRAMP01458
SequenceGIFTLFKGAAKLLGKTLAKEAGKTGLELMACKVTNQC
Length37
NameEsculentin-2V (Frogs, amphibians, animals)
SourceOdorrana hainanensis (Chinese frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Staphylococcus aureus FDA 209P (MIC=4.4 µM);##Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=2.8 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys31 and Cys37)
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16427248

Physicochemical Properties

Residues37
SequenceGIFTLFKGAAKLLGKTLAKEAGKTGLELMACKVTNQC
Molecular Weight3855.634
Grand Average of Hydropathy0.292
Isoelectric Point9.514
Charge at pH 7.43.496
Secondary StructureHelix: 0.270, Turn: 0.162, Sheet: 0.378
Instability Index-7.911
Aromaticity0.054

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