Basic Information
| ID | DRAMP01453 |
|---|
| Sequence | GIFSLFKAGAKFFGKHLLKQAGKAGAEHLACKATNQC |
|---|
| Length | 37 |
|---|
| Name | Esculentin-2LTa (Frogs, amphibians, animals) |
|---|
| Source | Hylarana latouchii (Broad-folded frog) |
|---|
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
|---|
| Pathogen | Gram-positive bacteria: Staphylococcus aureus ATCC2592 (MIC=1.6 µM), Bacillus licheniformis X39 (MIC=3.2 µM), Staphylococcus carnosus KHS (MIC=3.2 µM), Rhodococcus rhodochrous X15 (MIC=0.8 µM);##Gram-negative bacterium: Psychrobacter faecalis X29 (MIC=1.6 µM). |
|---|
| Hemolytic Activity | [Ref.22426384] LD50>600 μM against human erythrocytes |
|---|
| Cytotoxicity | No cytotoxicity information found |
|---|
| N-terminal Modification | Free |
|---|
| C-terminal Modification | Cyclization (Cys31 and Cys37) |
|---|
| Linear/Cyclic/Branched | Cyclic |
|---|
| Uniprot |
|
|---|
| PDB |
|
|---|
| 3D View | |
|---|
| PDB Download | Download PDB Predicted by Alphafold2 |
|---|
| PubMed ID | 22426384 |
|---|
