Basic Information

IDDRAMP01519
SequenceGVFSFLKTGAKLLGSTLLKMAGKAGAEHLACKATNQC
Length37
NameEsculentin-2PRa (Frogs, amphibians, animals)
SourceRana pretiosa (North American oregon spotted frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacterium: Escherichia coli;##Gram-positive bacterium: Staphylococcus aureus.##Yeast: Candida albicans.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys31 and Cys37)
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID21295070

Physicochemical Properties

Residues37
SequenceGVFSFLKTGAKLLGSTLLKMAGKAGAEHLACKATNQC
Molecular Weight3766.458
Grand Average of Hydropathy0.308
Isoelectric Point9.595
Charge at pH 7.43.534
Secondary StructureHelix: 0.243, Turn: 0.216, Sheet: 0.378
Instability Index7.514
Aromaticity0.054

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