Basic Information
| ID | DRAMP01470 |
|---|
| Sequence | GIFSLIKTAAKFVGKNLLKQAGKAGVEHLACKANNQC |
|---|
| Length | 37 |
|---|
| Name | Esculentin-2-ALb (Frogs, amphibians, animals) |
|---|
| Source | Amolops loloensis |
|---|
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
|---|
| Pathogen | [Ref.19843479]Gram-positive bacteria: Staphylococcus aureus ATCC2592 (MIC=1.25 µg/mL), Bacillus pumilus (MIC=2.5 µg/mL), Bacillus cereus (MIC=7.5 µg/mL);##Gram-negative bacteria: Escherichia coli ATCC25922 (MIC=12.5 µg/mL), Bacillus dysenteriae (MIC=7.5 µg/mL), Acinetobacter calcoaceticus (MIC=12.5 µg/mL), Psecdomonas aeruginosa (MIC=50 µg/mL);##Yeast: Candida albicans ATCC2002 (MIC=2.5 µg/mL). |
|---|
| Hemolytic Activity | [Ref:19843479] It has 17% hemolytic activity at 100 μg/mL against rabbit red blood cells |
|---|
| Cytotoxicity | No cytotoxicity information found |
|---|
| N-terminal Modification | Free |
|---|
| C-terminal Modification | Cyclization (Cys31 and Cys37) |
|---|
| Linear/Cyclic/Branched | Cyclic |
|---|
| Uniprot |
|
|---|
| PDB |
|
|---|
| 3D View | |
|---|
| PDB Download | Download PDB Predicted by Alphafold2 |
|---|
| PubMed ID | 19843479 |
|---|
