Basic Information

IDDRAMP01974
SequenceGIMRVFKGVLKTAGKSVAKNVAGSFLDRLKCKISGGC
Length37
NameBrevinin-2ZHa (Frogs, amphibians, animals)
SourceRana zhenhaiensis (Chinese brown frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacterium: Staphylococcus aureus ATCC 2592 (MIC=1 µM);##Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=5 µM), Pseudomonas aeruginosa ATCC 9027 (MIC=5 µM).##Yeast: Candida albicans ATCC 2002 (MIC=3 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22943778

Physicochemical Properties

Residues37
SequenceGIMRVFKGVLKTAGKSVAKNVAGSFLDRLKCKISGGC
Molecular Weight3840.629
Grand Average of Hydropathy0.276
Isoelectric Point10.318
Charge at pH 7.46.494
Secondary StructureHelix: 0.297, Turn: 0.270, Sheet: 0.189
Instability Index-8.841
Aromaticity0.054

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