Basic Information

IDDRAMP02025
SequenceGLFSVVTGVLKAVGKNVAKNVGGSLLEQLKCKISGGC
Length37
NameBrevinin-2DYe (Brevinin-2CDYa; Frogs, amphibians, animals)
SourceRana dybowskii (Dybovsky's frog) (Korean brown frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Staphylococcus aureus (MIC=15 µM);##Gram-negative bacterium: Escherichia coli (MIC=30 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys31 and Cys37)
Linear/Cyclic/BranchedCyclic
Uniprot P0C5X5
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17688900, 17698251

Physicochemical Properties

Residues37
SequenceGLFSVVTGVLKAVGKNVAKNVGGSLLEQLKCKISGGC
Molecular Weight3675.367
Grand Average of Hydropathy0.559
Isoelectric Point9.595
Charge at pH 7.43.497
Secondary StructureHelix: 0.351, Turn: 0.324, Sheet: 0.216
Instability Index3.249
Aromaticity0.027

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