Basic Information
| ID | DRAMP01875 |
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| Sequence | GLMSLFRGVLKTAGKHIFKNVGGSLLDQAKCKITGEC |
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| Length | 37 |
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| Name | Brevinin-2PRa (Frogs, amphibians, animals) |
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| Source | Rana pirica (Hokkaido frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.15003829] Gram-negative bacterium: Escherichia coli(MIC=6μM), Pseudemonas aeruginosa(MIC=3μM), Enterobacter cloacae(MIC=6μM), Klebsiella pneumoniae(MIC=6μM);## Gram-positive bacterium: Staphylococcus aureus(MIC=25μM);## Yeast: Candida albicans(MIC>100μM) |
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| Hemolytic Activity | [Ref.15003829] HC50=55 μM against human erythrocytes |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Cyclization (Cys31 and Cys37) |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 15003829 |
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