Basic Information
| ID | DRAMP01469 |
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| Sequence | GIFALIKTAAKFVGKNLLKQAGKAGLEHLACKANNQC |
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| Length | 37 |
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| Name | Esculentin-2-Ala (Frogs, amphibians, animals) |
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| Source | Amolops loloensis |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.19843479]Gram-positive bacteria: Staphylococcus aureus ATCC2592 (MIC=2.5 µg/mL), Bacillus dysenteriae (MIC=7.5 µg/mL), Bacillus cereus (MIC=7.5 µg/mL);##Gram-negative bacteria: Escherichia coli ATCC25922 (MIC=12.5 µg/mL), Bacillus pumilus (MIC=2.5 µg/mL), Acinetobacter calcoaceticus (MIC=25 µg/mL), Psecdomonas aeruginosa (MIC=50 µg/mL);##Yeast: Candida albicans ATCC2002 (MIC=2.5 µg/mL) |
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| Hemolytic Activity | [Ref:19843479] It has 22% hemolytic activity at 100 μg/mL against rabbit red blood cells |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Cyclization (Cys31 and Cys37) |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 19843479 |
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