Basic Information

IDDRAMP01915
SequenceGVLGTVKNLLIGAGKSAAQSVLKTLSCKLSNDC
Length33
NameBrevinin-2GRb (Frogs, amphibians, animals)
SourceRana grahami (Asian frog)
ActivityAntimicrobial, Antibacterial
PathogenNo MICs found in DRAMP database
Hemolytic Activity[Ref.16621155] LC50=180 μM against human erythrocytes.
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys27 and Cys33)
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16621155, 17272268

Physicochemical Properties

Residues33
SequenceGVLGTVKNLLIGAGKSAAQSVLKTLSCKLSNDC
Molecular Weight3289.864
Grand Average of Hydropathy0.439
Isoelectric Point9.308
Charge at pH 7.42.499
Secondary StructureHelix: 0.303, Turn: 0.303, Sheet: 0.273
Instability Index19.155
Aromaticity0

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