Basic Information

IDDRAMP02023
SequenceGIFDVVKGVLKGVGKNVAGSLLEQLKCKLSGGC
Length33
NameBrevinin-2DYd (Frogs, amphibians, animals)
SourceRana dybowskii (Dybovsky's frog) (Korean brown frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Staphylococcus aureus (MIC=15 µM);##Gram-negative bacterium: Escherichia coli (MIC=15 µM).##NOTE: mixture of Brevinin-2DYc/2DYd
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys27 and Cys33)
Linear/Cyclic/BranchedCyclic
Uniprot P0C5X4
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17688900

Physicochemical Properties

Residues33
SequenceGIFDVVKGVLKGVGKNVAGSLLEQLKCKLSGGC
Molecular Weight3317.962
Grand Average of Hydropathy0.491
Isoelectric Point9.243
Charge at pH 7.42.497
Secondary StructureHelix: 0.364, Turn: 0.303, Sheet: 0.212
Instability Index1.558
Aromaticity0.03

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