Basic Information

IDDRAMP02053
SequenceSVLGTVKDLLIGAGKSAAQSVLTALSCKLSNSC
Length33
NameLividin-3 (Brevinin-2-OR1; Frogs, amphibians, animals)
SourceOdorrana rotodora (Chinese odorous frog) (Odorrana livida)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Escherichia coli ATCC 25922 (MIC=5.5 µg/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=22 µg/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=11 µg/ml).##Yeast: Candida albicans (MIC=11 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys27 and Cys33)
Linear/Cyclic/BranchedCyclic
Uniprot Q2UXR2
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16713657, 22029824

Physicochemical Properties

Residues33
SequenceSVLGTVKDLLIGAGKSAAQSVLTALSCKLSNSC
Molecular Weight3235.77
Grand Average of Hydropathy0.682
Isoelectric Point8.84
Charge at pH 7.41.197
Secondary StructureHelix: 0.303, Turn: 0.303, Sheet: 0.303
Instability Index31.606
Aromaticity0

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