Basic Information

IDDRAMP02019
SequenceGLFDVVKGVLKGAGKNVAGSLLEQLKCKLSGGC
Length33
NameBrevinin-2DYb (Frogs, amphibians, animals)
SourceRana dybowskii (Dybovsky's frog) (Korean brown frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Staphylococcus aureus (MIC=30 µM);##Gram-negative bacterium: Escherichia coli (MIC=30 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys27 and Cys33)
Linear/Cyclic/BranchedCyclic
Uniprot P0C5X2
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17688900

Physicochemical Properties

Residues33
SequenceGLFDVVKGVLKGAGKNVAGSLLEQLKCKLSGGC
Molecular Weight3289.909
Grand Average of Hydropathy0.397
Isoelectric Point9.243
Charge at pH 7.42.497
Secondary StructureHelix: 0.333, Turn: 0.303, Sheet: 0.273
Instability Index4.13
Aromaticity0.03

Similar Structure Search

Candidates based on structure

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