Basic Information

IDDRAMP01260
SequenceALWKNMLKGIGKLAGQAALGAVKTLVGAES
Length30
NameDermadistinctin-Q1 (DD Q1; Frogs, amphibians, animals)
SourcePhyllomedusa distincta (Monkey frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacteria: Staphylococcus aureus (MIC=2.7 µM), Enterococcus faecalis (MIC=22 µM);##Gram-negative bacteria: Pseudomonas aeruginosa (MIC=5.4 µM), Escherichia coli (MIC=1.3 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.10477123]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedLinear
Uniprot P83641
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10477123

Physicochemical Properties

Residues30
SequenceALWKNMLKGIGKLAGQAALGAVKTLVGAES
Molecular Weight2996.569
Grand Average of Hydropathy0.47
Isoelectric Point10.002
Charge at pH 7.42.599
Secondary StructureHelix: 0.300, Turn: 0.233, Sheet: 0.433
Instability Index0.38
Aromaticity0.033

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