Basic Information
| ID | DRAMP01258 |
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| Sequence | ALWKTLLKNVGKAAGKAALNAVTDMVNQ |
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| Length | 28 |
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| Name | Dermadistinctin-L (DD L; Frogs, amphibians, animals) |
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| Source | Phyllomedusa distincta (Monkey frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal, Antiprotozoal |
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| Pathogen | [Ref.10477123]Gram-positive bacteria: Staphylococcus aureus (MIC=1.3 µM), Enterococcus faecalis (MIC=10 µM);##Gram-negative bacteria: Pseudomonas aeruginosa (MIC=40 µM), Escherichia coli (MIC=2.5 µM);##[Ref.17442605]Fungi: Candida tropicalis (MIC=10.9 µM), Candida guilliermondii (MIC=21.8 µM), Candida albicans (MIC=21.8 µM), Candida albicans ATCC 1023 (MIC=10.9 µM). |
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| Hemolytic Activity | [Ref:10477123]Show some hemolytic starting at 12.5 μM against human blood |
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| Cytotoxicity | [Ref.10477123]No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Free |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
P83639 |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 10477123, 12379643, 17409003, 17442605 |
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