Basic Information
| ID | DRAMP20816 |
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| Sequence | KILGKLWKGVKSIF |
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| Length | 14 |
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| Name | K1K8 |
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| Source | Synthetic construct |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.26952110] Gram-positive bacteria:Staphylococcus aureus AB94004 (MIC=6.25μg/mL), Staphylococcus aureus ATCC6538 (MIC=12.5μg/mL), Staphylococcus aureus ATCC25923 (MIC=12.5μg/mL), Staphylococcus aureus MRSA P1381 (MIC=6.25μg/mL), Staphylococcus aureus MRSA P1374 (MIC=6.25μg/mL);##Gram-negative bacteria: Escherichia coli AB94012 (MIC=25μg/mL), Escherichia coli ATCC25922 (MIC=50μg/mL), Pseudomonas aeruginosa AB93066 (MIC=50μg/mL), Pseudomonas aeruginosa ATCC9027 (MIC=50μg/mL) |
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| Hemolytic Activity | [Ref.26952110] 10% hemolysis at 400μg/mL against human red blood cells |
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| Cytotoxicity | [Ref.26952110] The cell vaibility of HFF cell lines is 100%, 108%, 105% and 38% at peptide concentrations of 0 μg/ml, 50 μg/ml, 100 μg/ml and 200 μg/ml. ##The cell viability of HEK293T cell lines is 105%, 125%, 101% and 21% at peptide concentrations of |
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| N-terminal Modification | Free |
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| C-terminal Modification | Amidation |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 26952110 |
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