Basic Information

IDDRAMP04002
SequenceILGKILKGIKKLF
Length13
Name[L6, K11]-IsCT (IsCT analog through amino acids substitution)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacteria: Escherichia coli KCTC 1682 (MIC=2 µM), Pseudomonas aeruginosa KCTC 1637 (MIC=2 µM), Salmonella typhimurium KCTC 1926 (MIC=1 µM);##Gram-positive bacteria: Staphylococcus epidermidis KCTC 1917 (MIC=1 µM), Staphylococcus aureus KCTC 1621 (MIC=2 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15369808

Physicochemical Properties

Residues13
SequenceILGKILKGIKKLF
Molecular Weight1470.927
Grand Average of Hydropathy0.869
Isoelectric Point10.478
Charge at pH 7.43.547
Secondary StructureHelix: 0.538, Turn: 0.154, Sheet: 0.231
Instability Index-6.854
Aromaticity0.077

Similar Structure Search

Candidates based on structure

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