Basic Information

IDDRAMP01621
SequenceIIGPVLGMVGSALGGLLKKI
Length20
NameBombinin-H1 (Frogs, amphibians, animals)
SourceBombina variegata (European frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.8223491]Gram-negative bacterium: Escherichia coli D21 (MIC=3.8 µM);##Gram-positive bacterium: Staphylococcus aureus Cowan 1 (MIC=2.1 µM).
Hemolytic Activity[Ref:8223491]Not determined hemolytic activity against human red blood cells.
Cytotoxicity[Ref.8223491]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot P82282, P82283
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID8223491

Physicochemical Properties

Residues20
SequenceIIGPVLGMVGSALGGLLKKI
Molecular Weight1936.448
Grand Average of Hydropathy1.43
Isoelectric Point10.003
Charge at pH 7.41.552
Secondary StructureHelix: 0.450, Turn: 0.350, Sheet: 0.300
Instability Index12.565
Aromaticity0

Similar Structure Search

Candidates based on structure

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