Basic Information

IDDRAMP01788
SequenceNILNTIINLAKKIL
Length14
NameTemporin-HN2 (Frogs, amphibians, animals)
SourceOdorrana hainanensis (Hainan odorous frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacteria: Staphylococcus aureus ATCC2592 (MIC=4.8 µM), Staphylococcus carnosus KHS (MIC=19 µM), Bacillus licheniformis X39 (MIC=19 µM),Rhodococcus rhodochrous X15 (MIC=2.4 µM);##Gram-negative bacterium: Psychrobacter faecalis X29 (MIC=37.5 µM).##Fungi: Slime mould 090223 (MIC=9.5 µM) and Candida albicans ATCC2002 (MIC=9.5 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.22450466]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot E7EKD4
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22450466

Physicochemical Properties

Residues14
SequenceNILNTIINLAKKIL
Molecular Weight1580.953
Grand Average of Hydropathy0.871
Isoelectric Point10.003
Charge at pH 7.41.552
Secondary StructureHelix: 0.500, Turn: 0.214, Sheet: 0.286
Instability Index56.057
Aromaticity0

Similar Structure Search

Candidates based on structure

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