Basic Information

IDDRAMP01790
SequenceFLSIIAKVLGSLF
Length13
NameTemporin-1Vb (Temporin 1Vb; Frogs, amphibians, animals)
SourceRana virgatipes (Ranidae) (Aquarana)
ActivityAntimicrobial, Antibacterial, Anti-Gram+
Pathogen[Ref.15996769]Gram-positive bacteria: Staphylococcus aureus NCTC8325 (MIC=5 µM), S. aureus (MRSA) T7/20 (MIC=10 µM), S. epidermidis RP62A (MIC=5 µM), Enterococcus faecalis ATCC 29212 (MIC=20 µM), Streptococcus group B HNTCC 80130 (MIC=20 µM).
Hemolytic Activity[Ref:15996769]LD50=30 μM against washed human erythrocytes
Cytotoxicity[Ref.15996769]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15996769

Physicochemical Properties

Residues13
SequenceFLSIIAKVLGSLF
Molecular Weight1407.738
Grand Average of Hydropathy2.008
Isoelectric Point8.75
Charge at pH 7.40.555
Secondary StructureHelix: 0.615, Turn: 0.231, Sheet: 0.308
Instability Index2.7
Aromaticity0.154

Similar Structure Search

Candidates based on structure

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