Basic Information
| ID | DRAMP18658 |
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| Sequence | FLPIVAKLLSGLL |
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| Length | 13 |
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| Name | Temporin-PE (Edible frogs, amphibians, animals) |
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| Source | Pelophylax kl.esculentus(Europe edible frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anitifungal, Anti-cancer, Anti-Gram- |
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| Pathogen | [Ref.29191658]Gram-positive bacteria: Staphylococcus aureus (MIC=2.0 μM), Methicillin-resistant Staphylococcus aureus (MIC=4.0 μM), Enterococcus faecalis (MIC=8.0 μM);##Gram-negative bacteria: Escherichia coli (MIC=16.0 μM);##Fungus: Candida albicans (MIC=4.0 μM).##Cancer cell lines: NCI-H157 (IC50=34.56 μM), U251MG (IC50=25.13 μM), PC-3 (IC50=38.56 μM), MDA-MB-435s (IC50=33.23 μM), HMEC-1 (IC50=58.62 μM). |
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| Hemolytic Activity | [Ref.29191658]HC50=39.64 μM against horse red blood cells |
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| Cytotoxicity | Not included yet |
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| N-terminal Modification | Not included yet |
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| C-terminal Modification | Not included yet |
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| Linear/Cyclic/Branched | Not included yet |
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| Uniprot |
A0A2H4WAJ8 |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 29191658 |
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