Basic Information

IDDRAMP01830
SequenceFLPIVGKLLSGLL
Length13
NameTemporin-1P (Temporin-1M; Temporin-1CSa; Frogs, amphibians, animals)
SourceRana pipiens (Northern leopard frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+
Pathogen[Ref.10651828] Gram-positive bacterium: Staphylococcus aureus (MIC=110 µM).
Hemolytic Activity[Ref.17451843] LC50 = 75 μM against human erythrocytes.
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal Modificationα‐Amidation
Linear/Cyclic/BranchedCyclic
Uniprot P82848
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10651828, 17451843

Physicochemical Properties

Residues13
SequenceFLPIVGKLLSGLL
Molecular Weight1369.733
Grand Average of Hydropathy1.8
Isoelectric Point8.75
Charge at pH 7.40.555
Secondary StructureHelix: 0.615, Turn: 0.308, Sheet: 0.385
Instability Index-2.077
Aromaticity0.077

Similar Structure Search

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