Basic Information

IDDRAMP01741
SequenceLLPIVGNLLNSLL
Length13
NameTemporin-D (Frogs, amphibians, animals)
SourceRana temporaria (European common frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+
Pathogen[Ref.9022710]Gram-positive bacterium: Bacillus megaterium
Hemolytic Activity[Ref.10691983]55% hemolysis at 10 μM, 90% hemolysis at 20 μM, 95% hemolysis at 40μM, 100% hemolysis at 60 μM against human red blood cells.
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P56919
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID9022710, 10691983

Physicochemical Properties

Residues13
SequenceLLPIVGNLLNSLL
Molecular Weight1378.698
Grand Average of Hydropathy1.669
Isoelectric Point5.525
Charge at pH 7.4-0.443
Secondary StructureHelix: 0.615, Turn: 0.385, Sheet: 0.462
Instability Index4.454
Aromaticity0

Similar Structure Search

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