Basic Information
| ID | DRAMP01739 |
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| Sequence | LLPIVGNLLKSLL |
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| Length | 13 |
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| Name | Temporin-B (Frogs, amphibians, animals) |
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| Source | Rana temporaria (European common frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.9022710] Gram-positive bacteria: Bacillus megaterium BM11 (LC=2.8 µM), Staphylococcus aureus Cowanl (LC=6.0 µM), Streptococcus pyogenes betahemolytic group A (LC=7.0 µM);##Gram-negative bacteria: Escherichia coli D21(LC=21.0 µM), Escherichia coli D21e7 (LC=13.2 µM), Escherichia coli D21f1 (LC=10.0 µM), Escherichia coli D21f2 (LC=3.3 µM), Escherichia coli D22 (LC=11.2 µM),Yersinia pseudotuberculosis (LC=7.0 µM), Pseudomonas aeruginosa ATCC15692 (LC>360 µM);##Yeast: Candida albicans (LC=4.0 µM).(LC: Lethal concentration).##[Ref.28443279] Gram-positive bacterium: S.aureus ATCC 33591 (MIC=12μM), Staphylococcus epidermidis (MIC=6μM);##Gram-negative bacterium: Klebsiella pneumoniae ATCC BAA-1706 (MIC=48μM), Pseudomonas aeruginosa ATCC 27853 (MIC=48μM) |
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| Hemolytic Activity | [Ref.9022710] LC>120 µM against Human red blood cells. (LC: Lethal concentration)##[Ref.28443279] 1% hemolysis at 96μM against human red blood cells. |
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| Cytotoxicity | Not included yet |
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| N-terminal Modification | Not included yet |
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| C-terminal Modification | Not included yet |
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| Linear/Cyclic/Branched | Not included yet |
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| Uniprot |
P79874 |
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| PDB |
6GIL |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 9022710, 28443279 |
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