Basic Information

IDDRAMP01732
SequenceFFPIVGKLLFGLSGLL
Length16
NameTemporin-ALe (Frogs, amphibians, animals)
SourceAmolops loloensis
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.19843479]Gram-positive bacteria: Staphylococcus aureus ATCC2592 (MIC=1.25 µg/mL), Bacillus pumilus (MIC=5 µg/mL), Bacillus cereus (MIC=15 µg/mL);##Gram-negative bacteria: Escherichia coli ATCC25922 (MIC=1.25 µg/mL), Bacillus dysenteriae (MIC=5 µg/mL), Acinetobacter calcoaceticus (MIC=15 µg/mL), Psecdomonas aeruginosa (MIC=5 µg/mL);##Yeast: Candida albicans ATCC2002 (MIC=1.25 µg/mL).
Hemolytic Activity[Ref:19843479]10% hemolytic activity at 100 μg/mL against rabbit red blood cells
Cytotoxicity[Ref.19843479]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID19843479

Physicochemical Properties

Residues16
SequenceFFPIVGKLLFGLSGLL
Molecular Weight1721.132
Grand Average of Hydropathy1.788
Isoelectric Point8.75
Charge at pH 7.40.555
Secondary StructureHelix: 0.625, Turn: 0.312, Sheet: 0.312
Instability Index0.188
Aromaticity0.188

Similar Structure Search

Candidates based on structure

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