Basic Information

IDDRAMP01818
SequenceNFLGTLVNLAKKIL
Length14
NameTemporin-1CSd (Temporin-1DRb; Frogs, amphibians, animals)
SourceRana cascadae (Cascades frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacterium: Escherichia coli (MIC=64 µM);##Gram-positive bacterium: Staphylococcus aureus (MIC=16 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.17451843]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17451843

Physicochemical Properties

Residues14
SequenceNFLGTLVNLAKKIL
Molecular Weight1543.891
Grand Average of Hydropathy0.9
Isoelectric Point10.003
Charge at pH 7.41.552
Secondary StructureHelix: 0.500, Turn: 0.214, Sheet: 0.357
Instability Index0.179
Aromaticity0.071

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.