Basic Information

IDDRAMP01956
SequenceGFKGAFKNVMFGIAKSAGKSALNALACKIDKSC
Length33
NameBrevinin-2PTb (Frogs, amphibians, animals)
SourceRana picturata (Malaysian fire frog) (Hylarana picturata)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=9 µM);##Gram-negative bacterium: Escherichia coli ATCC 25726 (MIC=9 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys27 and Cys33)
Linear/Cyclic/BranchedCyclic
Uniprot P0C8T4
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID18621071

Physicochemical Properties

Residues33
SequenceGFKGAFKNVMFGIAKSAGKSALNALACKIDKSC
Molecular Weight3377.011
Grand Average of Hydropathy0.273
Isoelectric Point9.789
Charge at pH 7.44.494
Secondary StructureHelix: 0.242, Turn: 0.273, Sheet: 0.273
Instability Index8.345
Aromaticity0.091

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