Basic Information

IDDRAMP01958
SequenceGFLDSFKNAMIGVAKSAGKTALNTLACKIDKTC
Length33
NameBrevinin-2PTd (Frogs, amphibians, animals)
SourceRana picturata (Malaysian fire frog) (Hylarana picturata)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Staphylococcus aureus ATCC 25923;##Gram-negative bacterium: Escherichia coli ATCC 25726.
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys27 and Cys33)
Linear/Cyclic/BranchedCyclic
Uniprot P0C8T6
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID18621071

Physicochemical Properties

Residues33
SequenceGFLDSFKNAMIGVAKSAGKTALNTLACKIDKTC
Molecular Weight3418.015
Grand Average of Hydropathy0.233
Isoelectric Point9.243
Charge at pH 7.42.497
Secondary StructureHelix: 0.242, Turn: 0.212, Sheet: 0.273
Instability Index14.003
Aromaticity0.061

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