Basic Information

IDDRAMP01957
SequenceGLLDSFKNAMIGIAKSAGKTALNKIACKIDKTC
Length33
NameBrevinin-2PTc (Frogs, amphibians, animals)
SourceRana picturata (Malaysian fire frog) (Hylarana picturata)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC>72 µM);##Gram-negative bacterium: Escherichia coli ATCC 25726 (MIC=18 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys27 and Cys33)
Linear/Cyclic/BranchedCyclic
Uniprot P0C8T5
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID18621071

Physicochemical Properties

Residues33
SequenceGLLDSFKNAMIGIAKSAGKTALNKIACKIDKTC
Molecular Weight3425.094
Grand Average of Hydropathy0.197
Isoelectric Point9.514
Charge at pH 7.43.494
Secondary StructureHelix: 0.242, Turn: 0.212, Sheet: 0.273
Instability Index18.606
Aromaticity0.03

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.